Summer 2025 - Small Molecule Drug Discovery Internship
Company: Disability Solutions
Location: San Diego
Posted on: October 19, 2024
Job Description:
Working with UsChallenging. Meaningful. Life-changing. Those
aren't words that are usually associated with a job. But working at
Bristol Myers Squibb is anything but usual. Here, uniquely
interesting work happens every day, in every department. From
optimizing a production line to the latest breakthroughs in cell
therapy, this is work that transforms the lives of patients, and
the careers of those who do it. You'll get the chance to grow and
thrive through opportunities uncommon in scale and scope, alongside
high-achieving teams rich in diversity. Take your career farther
than you thought possible.Bristol Myers Squibb recognizes the
importance of balance and flexibility in our work environment. We
offer a wide variety of competitive benefits, services and programs
that provide our employees with the resources to pursue their
goals, both at work and in their personal lives. Read more:
.Position SummaryThe Lead Discovery Optimization department in San
Diego is seeking a highly motivated undergraduate student to join
our 10-week internship program. Our team is dedicated to developing
state-of-the-art platform technologies and innovative cell-based
assays that drive the discovery of novel small molecule
therapeutics for areas of unmet medical need. We primarily focus on
delivering modalities of targeted protein degradation (TPD), which
repurpose endogenous ubiquitin ligases to mediate the proteasomal
degradation of disease-causing proteins.A successful candidate will
have a basic understanding of cellular protein homeostasis pathways
and a keen interest in learning more about TPD and drug discovery
processes. This position will involve designing and executing
lab-based experiments to develop robust and scalable cell-based
assays for evaluating the on-target engagement of our hit-to-lead
compounds.Key Responsibilities
- Shadow and gain hands-on experience with cell line engineering
techniques, such as transfection, lentiviral particle preparation,
and transduction.
- Characterize cell lines using Western Blot and bioluminescence
reporter assays.
- Regularly maintain mammalian cell lines.
- Shadow, perform, and optimize cell-based assays, including but
not limited to protein-protein interaction assays, fluorescence or
bioluminescence reporter assays, and cell proliferation
assays.
- Maintain diligent lab notebook records; communicate research
progress and troubleshoot issues with your mentor and team
members.
- Present your project findings to peers and colleagues at the
end of the internship.Qualifications & Experience
- Strong interest in drug discovery and targeted protein
degradation (TPD).
- Proficiency in Microsoft Office programs, including Excel,
Word, and PowerPoint.
- Familiarity with mammalian cell culture is preferred.
- Experience with cell-based assays is desirable but not
required.The starting compensation for this job is a range from
$21.00/hour - $29.00/hour. The starting pay rate takes into account
characteristics of the job, such as required skills and the
geographic location where work is performed. Final individual
compensation is decided commensurate with demonstrated experience
and education level.If you come across a role that intrigues you
but doesn't perfectly line up with your resume, we encourage you to
apply anyway. You could be one step away from work that will
transform your life and career. Uniquely Interesting Work,
Life-changing CareersWith a single vision as inspiring as
Transforming patients' lives through science--- , every BMS
employee plays an integral role in work that goes far beyond
ordinary. Each of us is empowered to apply our individual talents
and unique perspectives in an inclusive culture, promoting
diversity in clinical trials, while our shared values of passion,
innovation, urgency, accountability, inclusion and integrity bring
out the highest potential of each of our colleagues.On-site
Protocol BMS has a diverse occupancy structure that determines
where an employee is required to conduct their work. This structure
includes site-essential, site-by-design, field-based and
remote-by-design jobs. The occupancy type that you are assigned is
determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned
facility. Site-by-design roles may be eligible for a hybrid work
model with at least 50% onsite at your assigned facility. For these
roles, onsite presence is considered an essential job function and
is critical to collaboration, innovation, productivity, and a
positive Company culture. For field-based and remote-by-design
roles the ability to physically travel to visit customers, patients
or business partners and to attend meetings on behalf of BMS as
directed is an essential job function. BMS is dedicated to ensuring
that people with disabilities can excel through a transparent
recruitment process, reasonable workplace
accommodations/adjustments and ongoing support in their roles.
Applicants can request a reasonable workplace
accommodation/adjustment prior to accepting a job offer. If you
require reasonable accommodations/adjustments in completing this
application, or in any part of the recruitment process, direct your
inquiries to . Visit to access our complete Equal Employment
Opportunity statement. BMS cares about your well-being and the
well-being of our staff, customers, patients, and communities. As a
result, the Company strongly recommends that all employees be fully
vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest
and conviction records, pursuant to applicable laws in your area.If
you live in or expect to work from Los Angeles County if hired for
this position, please visit this page for important additional
information: Any data processed in connection with role
applications will be treated in accordance with applicable data
privacy policies and regulations.
Keywords: Disability Solutions, Temecula , Summer 2025 - Small Molecule Drug Discovery Internship, Other , San Diego, California
Didn't find what you're looking for? Search again!
Loading more jobs...